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Enjoy Real Texan Hospitality at our Amarillo, TX Hotel No matter what brings you to the Texas Panhandle, you'll find the finest hospitality in Texas at the Holiday Inn Express ? Hotel & Suites in Amarillo, TX. Our hotel is located off I-40, close to R. Husband International Airport (AMA), downtown Amarillo and area attractions like Palo Duro Canyon. Business guests appreciate our Amarillo, Texas hotel's location near companies like Bell Helicopter, Pantex, Tyson Foods and area hospitals. We also boast free Internet access, stylish executive suites, a 24-hour Business Center and two meeting rooms to make life on the road simpler. Families enjoying a Texas vacation love affordable hotels in Amarillo, TX that are close to must-see attractions like the Panhandle Plains Museum, the American Quarter Horse Museum and Wonderland Amusement Park. The iconic Cadillac Ranch is also just 15 miles from our Amarillo, Texas lodging. Few hotels in Amarillo, TX can match our amenities and ambiance. From the unexpected waterfall in our lobby to freshly updated, smoke-free rooms with a microwave, fridge and a wet bar, you'll enjoy our great value. We offer a sparkling, indoor pool, a Fitness Center with a flat panel TV and a free breakfast buffet is served each morning. We're also one of the most affordable hotels in Amarillo, TX with hot tub suites. Stay Smart with our Amarillo, Texas hotel's great values on your next Texas vacation or business trip.